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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5880d739dc76c2e56b0c23d3b21caddba6eb2043e9c9a40aa35dbb0d2d946268' 
  AND token = '4Gznhl+C2Dg25aUivHniXNN3LmfDHXPdlLq23rqcU6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}