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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f686fe6c46bc621054b693f3c3ed552192ce1df96018e2e4e11e1346da18a152' 
  AND token = '6OVHN13wXzEiMS+MQj4opkCmvbKlB4Smkp+F6GPIe/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}