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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4559ea0a820decf5d6d105cfd246025615e392de8207f2dbf7ed49f7d1418b5' 
  AND token = '4P1EFktoTtWMa8myj8x0vkevYlfvrnwk955kObP8w0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}