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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f93a557caa04f4d8dc3767e6f818c1856b2025f872a3e1148490f9d25a76aa' 
  AND token = 'hxW0JzXeJZN7vxac53GGXlzDE7N11k2hBHDm3AsDHig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}