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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59871462d7b3460c0a286792e3adf3994ad43ff4eeb48894ac84b8248dbfc66b' 
  AND token = 'MqNj87TW02Fqs2HKLqNtzaBFEmlDkWhQPHkhVBUDyp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}