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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d177e8d2268c1e3fa8eb1188b1b893e8c002ed64c8ec447bc63e28a0c8356e' 
  AND token = '0Z6BA2pviXwuvaOsZj9uZi7WkTDsChshKrhLDc54fy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}