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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72820a6fb582bdd5258c1eb9736287cc38bef5212d3f396dc44beefb2b35d714' 
  AND token = 'exrQDCsUT4JJYh6SmlkL0cDITEvQs7NALzAE0uPMsJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}