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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f578e05d6d2ab543c1c81ddc0574a2de832add06eb1127f9a87e2bc786d22bb8' 
  AND token = '0FZtQdVI6gcYNGP6ooDX1iBZ05vkai5ibEMCfpNQJ5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}