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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a629cdb9bedfc4b0f0cdb34d727cb2703e3eb798d35e0eef543694a320cefaa' 
  AND token = 'ayx3qTkdq9nOKPkCbzZMctHpjWJkunvnmfks+mv9Y7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}