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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a11a53fa644fb87155b87e2482bb5a5f07cad2f9c2bd06b75af5d6fa424d22d' 
  AND token = 'i6X5jB/FKvmuTpp/bIaOXwa8Ow8/qVgyEm0pz6MV7m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}