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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c85d04b36568d610870bb54ee87c75826fa8d36aa3cda3ddd96d54773e9d93' 
  AND token = 'dSEt1zu+ZZVR5ieEKqjZ+uBGTlMrQKIWvgcXrb3qffE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}