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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c1cf947af3d91852d801d7f2fd878909e3a3a1820076cd009a85e23857c6c5b' 
  AND token = 'T5tDwKC/2ji8TJnvsmfMF8wt+T5UbHY3l/dldPHTLsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}