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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420d5b0b22a149998c8639bfe0091211c7f6604f218969f87b451a58bc3a87a0' 
  AND token = '7/6/WIgwKTJyX51a4OAPN1u9p7T+j5ZtG3HtPuuEGa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}