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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e860b57777c0585d9edb52c53312af34058da01689fbd3b2669a61b71c8aff7a' 
  AND token = 'Ug+bfJdBpoCxIyCLUjbbJ1pDE4oEHrh7qfyKDtExS9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}