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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54f2de45f7def39da2b7e662cce84f1463c594c3964eec492a0f42e494ec40e9' 
  AND token = 'geU8cV64wW0UR2+OZzct6OkCXs/CVcF1IJguTyXY1V4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}