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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e89626a7a27b424a9229a00461337534166a9bedfb79b3159cbe07b399c01af' 
  AND token = 'vWhKAfUy+09IsKGTj/yHS2l4FYzL0ZSb9emAVuILVUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}