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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72984a55af8090818f09e6669230fd49e1e3b2019787ca595f99d57bbe70dfb' 
  AND token = 'F4gBUGwP8dABR41zuy4z8aQOnm3XGOETHU3W68UAA7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}