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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf0dfe27c43cae43116fbd9bbeefff541bc53518f4aec3f36df9a12348841a67' 
  AND token = 'cbXeYgnUDLKkFha96T4aJ3O+Uh9pG5mVaZVy7YKSPgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}