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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2239ad68150e402bfe5327a0e722c0544fe0f60f7ccce4dc9b7242691e32a94' 
  AND token = '2r0pSebekf/rC1g9wjWJrK6vTBLZd55G4pK6b50pJfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}