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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d8c996b43f49b850285e9c6c98e84de28e920437fc1413a98941eecf8be54c' 
  AND token = '2te/4z7bGxGnEpXW/w5N3Phs0g2JH+n0qcZEG0lFmFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}