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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a1cc8a0c70ddcd999c79ed71d518653184e14a23cef0a246b3e9af99b629bd' 
  AND token = 'sJMf7hmXbXidWinMwRrpEI+Fni0pbTugIx66INRIz6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}