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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3e597802286c61fea17f2084079fff4fac15c276924f2869191d8e4b4f62781' 
  AND token = 'M9SfVyP8Leq0/AMhyMS3N4Yfgq9+/YJvJ3/cwegxuo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}