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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd59ee08a5603e5499f35abdac38c9edea9bcd4d74bb49ce59cfd61a77251de06' 
  AND token = 'azLz//DE0qzp1umYwbz3OPXmb26nuxnQB4yOpEc6qJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}