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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2544d1f097c83ebeada901a62f9bb6f1b4d7df9c6cc76d65cd7469d91cbeb863' 
  AND token = 'Sd5K00fzFJr169GGxg1JxpoXtHiRxTwIKvBo1KNhnek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}