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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17fc7f7dbba0bd59d4bc514c0fab32beb8fac6c9bc448a5eb4a79ea37bc8f42c' 
  AND token = '+yuNHLe1yy1pnMeL4tqKv3uIfWboOt+2uSuH/u9d9oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}