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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88a69d4ccd29a0db027a6dc78f7d79514e338360cc85187a8b137c6e92698a73' 
  AND token = 'zmzZSizwBD2WG0LM03zCAKnqyeuv1uXIAZ7tpUPqzrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}