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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ce7cae3f96facfb56e2e5704844a4dd59a0e3f1cda426d274b460c6cf6bb383' 
  AND token = '20PS7YGJY1Og1SKQgIEwDTsvlOaLDvHJLOY3UsA4nks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}