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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09d1ed98594ec08e78b9046ca643185bf0f9500ba3dc198808c09acf01d53ffc' 
  AND token = 'UyY8R42jSdSmxkHY0V/rZG2ofjZ8rXUsCSIf3UKA/Ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}