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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75e0d107281ffa7367a6d083f1112efda8a9421dbd299fd34ede25c98395850a' 
  AND token = 'DT/Uw9weryLIJhN+nqsg74hTimsRLVCf2fmdbj3kty8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}