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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4d181e2983c6891ffbbd3698fc3f67c0693a36d5a5a1652cee8813df021855' 
  AND token = '+n9OBwqzry9hQNFbv7wwAes0FuRz8N5OxJjzWib5iZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}