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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f34081fc5e20a53100e3addfe70d417ada3ca1076a21abfb10ee03acc21c6c4' 
  AND token = 'OB4lRBcHhqCGe+XQSe5+Uw/vnolU59ggU5tGNcR+HSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}