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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '019d8b5d3a9e5a01c9df4f84305e2425dad6d7455c28e7a91dc5e7a0472e1ba8' 
  AND token = 'IP9lbm2aKQtNQkpg2vNC3OGZwgaEE545CY+hBPFWgk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}