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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d17dfa2798d2a787a18cce86ca0deb37c8a6332ecf0d073bc29c52cba130565' 
  AND token = 'ICBug86u/1e1zzv0P7C3iIlFNUjfP0O1N9L70kIfoJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}