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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f8ffaf4697dc7e52db14beeaeb6feb06b1e453cb3ee5a06feed417776d7c8d' 
  AND token = 'uFc6PQMTJwmfe3Yw6vTO3m/hOuzR00pEdRzWli786J0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}