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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be80dbaf207bf75f846bbf8f00a49e44e94b3d3c0de775746ec17b42074e558e' 
  AND token = '++qtlEFpTxzphYbE3kRSk0uHkVswISEB1d3+v8rdy/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}