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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e996ca210ba4147f1eee99de7942259105bd1b8a8dd5ff8017ab717f2e730bb' 
  AND token = '9uRdHr2Fwe6n7K+MTXK9teDA7ynm8fhD8mUtxQWGGKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}