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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1f21ba9d41179423e2e06bb29d3b2cae962b1b20b4b51993224b5eae7614e40' 
  AND token = '3glceWOeANh/wX+87VGYLCCpafHDLfwUQTLY/aKtii8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}