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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '599425ffd0d4eb084b1a204c8886c06e4a85b29e237cdb8e6045a8f2823b63a4' 
  AND token = 'eURnQO+Sc+LnAGwCsPPheLB4y136zAWPV3oM7W0vLr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}