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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc74abcb196484ce54c250a27d911a58e05db7e161ce3a664ddaf51b657dfe0c' 
  AND token = 'PYvRjE4BrdE4HtgYDL+miWU9EMOTGIdMq+Qyzb8JOwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}