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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9521da624e04cf3a5fa9e296aa8f2ee8a6bd13ed82be54d2280b7586ac0dcda8' 
  AND token = 'o/TWZKSJpwN8WScCaH0aTLtnxe9pWqfJhLG9v6XQKoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}