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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3a28362008da859e5a03e09b0b11e7c75319d467ef6b7e38a75563ea2e07a9' 
  AND token = 'XgdPfTuCAPendX96hFBn5XTIxemfED2kDT5aEMgVxWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}