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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86a24fcea141f6eb8454c1644b415020651af14b440db73182fb8668ea4f37ed' 
  AND token = 'BAW4a8a2F+tCAqBDeUeC+mwrKIeU49UOC7vjIoF3OKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}