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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abd48a250efcc8e3d0eb6556baca4bdfbe2271e13d39c15e3405d95b34d1cb37' 
  AND token = '4NL6Jfz6W0PUq4PCI8dqTIyV5r+0iHKd4MNwS7MWfRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}