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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d73e994c0d941838d9e0c9455d61d1c3548cbe138c2ec0464d1714fccf29bb' 
  AND token = 'cuXm4OiCqoSC6IKDVFUU6oi3HqjrPgC/v+ICP0NUmho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}