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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7acd4d80006ef4b61c23e26e45686aaae7c51bc2d6f7e3b242017a0d7408b693' 
  AND token = 'YajHWPtk+5B2R4dhbPOznRD6d0qBYIHoTmpDatrAK1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}