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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad6d5cbd69be6c9cb771351dde999babb7ec9f2f9426fe8ce8c8cbaebeff585a' 
  AND token = 'kND/wVxTtc7vKz8jW4SU6OKZCTYUDad5nKPnDCRD/Eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}