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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '725b3bda48e9fba9d4424c541a2d18755c62900d79f0ea3e9ef92f644eaeb562' 
  AND token = '3FGHShQBMt2ficYGgZxm/MUCnRmnImmxJ7Bmh99ChOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}