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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae3201dc56aab967e3244609e0023a382d2e2335b89caecb1f1223f963ff5c3e' 
  AND token = 'nVxR1rN/ifBE2FQmWv5Spb69XtsfuMl3eBS7lbkYFao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}