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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5db16ed18a8eb376332e17fdfc5014d4024bcfaf65b8d9fb498886cde1d50f' 
  AND token = '2AGr8Ce69r5SjOT9p0UMvmc0QoTrPtGs69CtRhxrOmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}