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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7165b2f6bb81963bf7c41c610e130a2a457ca698f659d2701a090dd6426118c2' 
  AND token = 'CV6oK+dc6I5dMuQRwvS/0GIbUhIaR5+7UuZCjIkkpeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}